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Duchenne muscular dystrophy, Jacob recovery

Dr. Nikonov
Dr. Nikonov

At the time of contacting me, Jacob has the diagnosis of Duchenne muscular dystrophy, confirmed by genetic research.

 

Child complaints: difficult walking the stairs, rising from the floor, does not run, as there is a great weakness that stumbles endlessly. In addition, muscle fatigue forces Jacob to sit down and rest after a few steps.

The first signs of the disease in the form of muscle weakness appeared in Jacob at the age of 2 years.

By the age of 6, Jacob developed a typical "duck gait" ((Waddling Gait) - swinging in the hip joints. In addition, pseudohypertrophy of the gastrocnemius, deltoid and gluteus muscles was formed.

Jacob says that he has weakness in the lower back, in the legs, in the soma, and in his hands. Over the past year, the child’s parents have noted the strengthening of their son’s weakness and are alarmed. As Jacob is a citizen of Ireland, his parents turned to Irish rehabilitation centers, where doctors told them that Duchenne muscular dystrophy is not treated, they offered steroid treatment (as recommended by the World Health Organization). But Jacob's parents, knowing that steroids may not very well affect the work of the internal organs, refused to use them.

Jacob's Duchenne muscular dystrophy has arisen due to a spontaneous mutation of a gene region that produces dystrophin protein. That is genetic disease was not transmitted from the mother, since the genetic analysis of Jacob's mother did not reveal the damaged gene.

Dr. Nikonov
Dr. Nikonov

When Jacob's parents turned to me, Nikolai Borisovich Nikonov, with a request to help their son, I replied that I could not influence the changed gene. So I can't help the muscle cell produce enough dystrophin.

But I can help the muscle cell to start getting rid of the extra lumps of fat accumulations, of which there are a very large number in the cell.

 

In Duchenne muscular dystrophy, mitochondria, which give energy to the motor proteins of the cell, are not in their places, but accumulated on the periphery of the cell membrane.

The entire space inside the cell between the motor proteins is occupied by fat accumulations. Even if give energy with the help of drugs to motor proteins, they will not be able to reduce due to the fact that the fat accumulations clamped them as a press.

So, if you reduce the amount of fat accumulations inside the muscle cell, that the mitochondria return to their jobs. The mitochondria will resume the supply of energy to the motor proteins, which by this time will not be compressed, and the muscles will begin to move. The more mitochondria will return, the more powerful the energy will be, the stronger the muscle will be.

muscle cell

Healthy cells are covered with a thin membrane called endomysium, but the invaded tissue around the muscle cells are increasingly filled with fat or fibrous cartilage tissue. This is called endometrial fibrosis.

Because macrophages understand that something is wrong, they penetrate into the swelling zone, and initiate an immune response that causes swelling. Swelling weakens the damaged cells even more and reduces their number. The process of reducing muscle cells is slow, which explains the progressive weakening pathology of the disease. Dead cells are usually replaced by a matrix of white tissue.

Dr. Nikonov
Dr. Nikonov

I thought, if you squeeze this swelling by my method, then it is possible to reduce its negative impact on muscle cells.

Using the example of the effect on muscle swelling in Jacob, I show a positive result in the appearance of force in the muscles. The first procedures I performed for Jacob were the most difficult.

 

Doctor and parents photo

Before the procedure, I achieved a good disposition towards myself, having established contact with Jacob. To build relationships with a child who is 6 years old, who does not speak and does not understand the Russian language, in addition, he is frightened by the previous effects of medical workers in other rehabilitation centers is very difficult.

But as a result of establishing contact and feeling the painlessness of the procedures I was conducting, Jacob began calling me a “magic doctor” - a magic doctor.

In consultation procedures, in order to distract a child from unpleasant sensations, need to constantly communicate with him. Only then he understands that the doctor will not hurt.

Мy wife Liliia Aleksandrovna Nikonova took part in the consultation-procedures. She, knowing English, translated the boy's questions. I answered Jacob, but since I was all focused on restoring muscle contractility, my answers were supplemented by my wife and Jacob’s mother.

I, Nikolai Borisovich Nikonov, Jacob's mother, relatives of the patient, and my wife took part in the procedures.

Photo of Jacob and flowers

The result of my exposure to the Jacob`s muscles

  1. Jacob stopped getting tired when walking long distances. Now he can walk all day!
  2. The child began to climb and descend the stairs without using his hands.
  3. The boy can climb the forest path to a height of 500 meters.
  4. He began to descend from a steep mountain without using his hands.
  5. Jacob runs without tripping.
  6. Squats and gets up from the squat without hands.
  7. Comes into the sea and stands with the force of a wave height of 2 points.
  8. Jacob walks along the large-pebble beach without support and rather quickly.
  9. The child has improved character: became open, sociable, began to speak more both in dialogue and in a monologue.
  10. He wanted to learn Russian to communicate with me, not in English, but in my native language.

 Jacob and mother at sea

the doctor, the wife and Jacob at the bushes

Duchenne muscular dystrophy. Nikonov Nikolai Borisovich, Nikonova Liliia Aleksandrovna, Jacob with his mother.

Jacob has a positive dynamic in restoring muscle strength.
Dr. Nikonov
Dr. Nikonov

Grateful to my wife Nikonova Liliia Aleksandrovna.

I am proud of the result!

I am proud of my knowledge!

 

What is Duchenne, Becker muscular dystrophy - video

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